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As a powerful nootropic, Modafinil helps improve memory, concentration, neural activity, and performance. Therefore, many take it as an energy drink. And this drug can actually be very helpful when it comes to performing tasks that require increased concentration, attention and staying awake for extended periods of time. In addition, modafinil improves mood and increases motivation.

Modafinil affects the brain by activating various biochemical processes in it. In particular, it stimulates the production of dopamine and related neurotransmitters, which indirectly increases the activity and improves the response (control functions) of the brain. These changes allow a person to solve mental problems more effectively, make quick decisions and maintain concentration for a long time. You can get more information on this subject from the article “The Effects of Modafinil: What to Expect While Taking the Drug”.

Modafinil is a drug belonging to the group of drugs with an exciting effect. This means that when it is used in a person, vigor increases due to the stimulation of the respiratory tract, blood circulation and part of the medulla oblongata. This analeptic is often used to combat drowsiness or narcolepsy.

Modafinil is also classified as a psychostimulant and was developed in the late 1980s to treat narcolepsy. This is a disease in which people can suddenly fall asleep during the day. It is still used for the same purposes in about 20 countries.

Course with Modafinil for men

Mechanism

Despite intensive research on the interaction of modafinil with a large number of neurotransmitters, the exact mechanism or set of mechanisms of interaction remains unclear. It is likely that modafinil, like other stimulants, increases the release of monoamines – especially the catecholamines norepinephrine and dopamine – from the synaptic clefts. However, modafinil increases the level of histamine in the hypothalamus, which has led some researchers to consider modafinil more of a “drowsiness remedy” than a classic amphetamine-like stimulant.

Studies show that modafinil “has a low potential for serious abuse” and “does not develop addiction among first-time users.” The combined effect of modafinil on both the catecholamine and histamine pathways reduces the potential for abuse compared to traditional stimulant drugs, while maintaining efficacy as a sleep medication.

Mechanism

Drug for men

Modafinil is used by those who need to increase concentration and performance, primarily IT people, businessmen and students. In 2019-2021, modafinil purchases increased 10-fold, not to mention how many people order it from online stores like HealthFit. Those who have taken this drug are quite pleased with the results. Reviews indicate that modafinil dramatically improves performance, increases concentration, removes the feeling of the city and is not addictive. The good reputation of modafinil has led to the fact that it began to be used by people suffering from depression, chronic fatigue, multiple sclerosis and any diseases in which there is prostration. What could be better than just taking a pill and being energetic all day long?

Several countries’ militaries are expressing interest in modafinil as an alternative to amphetamines, drugs traditionally used in combat situations where troops face sleep deprivation, such as long missions. The French government noted that the Foreign Legion used modafinil during certain covert operations. The UK Department of Defense has given directions to investigate QinetiQ modafinil and has spent 300,000 euros on one study. In 2011, the Indian Air Force announced the inclusion of modafinil in the plans[13]. The Indian Armed Forces Medical Service is investigating its use.

In the US Army, modafinil has been approved for use in several Air Force operations and is being studied for other uses. One study of helicopter pilots suggested that 600mg of modafinil in 3 doses could be used to maintain pre-deprivation responsiveness and accuracy for 40 hours without sleep. However, there was a significant level of nausea and dizziness. In another study of combat pilots, modafinil at three divided 100 mg doses was shown to maintain flight control accuracy in sleep-deprived F-117 pilots of about 27% of baseline for 37 hours without any significant side effects. In a study of 88 hours of sleep deprivation simulating military operation, the 400mg/day dose was mildly beneficial in maintaining combat readiness and performance under placebo control, but the investigators concluded that this dose was not high enough to offset much of the effect of total sleep deprivation.

The Journal of the Canadian Medical Society reported that modafinil has been used by astronauts on long missions to the International Space Station. Modafinil is “available to the crew to optimize fatigued performance” and helps with disruptions in circadian rhythms and decreased quality of sleep in astronauts. During high-risk, large-scale and long-term police operations, field doctors in Maryland (USA) may dispense 200 mg of modafinil once daily to law enforcement officers to improve attention and concentration and facilitate functioning with limited rest periods.

Until recently, there were doubts that this drug affects our mind. A recent study found that people who take modafinil score much higher on screening tests than those who take placebo pills. Some note that the drug also enhances physical endurance, and not only helps in mental work.

The breakdown and inability to fully work due to internal processes in the body. The main reasons for the decline in performance are chronic inflammation, fast food, the consumption of huge amounts of coffee and various drinks with artificial fillers.

Taking modafinil is the way to improve yourself. Such remedies do not need to be used on an ongoing basis, but only when additional energy and vitality are needed. It is also worth paying attention to normal nutrition and proper rest.

When it comes to the dosage of modafinil, everything is very individual.

Drug for men

Dosing

However, many adhere to the scheme, which will be discussed later.

50 mg modafinil This is the ideal dosage for most people who take this drug during the work week. This is a small dose, but it is enough to get a “kick” and a charge for the next 4-6 hours. Adhering to this dosage, a person feels alert, concentrated and full of energy throughout the working day, while the regimen and quality of sleep are not disturbed. Side effects on the background of such a dose usually do not appear.

75 mg armodafinil This is a stronger dose than 50mg modafinil. The effect of the drug will last for 5-7 hours or more. A person feels more alert, concentrated and able to solve complex problems. The risk of side effects with this dosage is minimal.

100 mg modafinil 100mg of modafinil is slightly stronger than 75mg of armodafinil. The positive effect of the drug persists for 8 hours or more. This is the ideal dosage if you need to do a lot of work without feeling tired, but at the same time fall asleep easily after midnight. A side effect at this dosage, if it happens, is manifested by minor symptoms.

150 mg armodafinil This is the usual full dose of this type of drug. After taking armodafinil at this dosage, wakefulness persists for 10-12 hours. As a rule, does not cause side effects. In rare cases, insomnia or dehydration may occur.

200 mg modafinil This is the gold standard when it comes to noticeably improving cognitive performance. For many, against the background of such a dosage, an increased concentration persists for 12 or more hours. Adverse reactions are rare, in some cases insomnia, headaches, dehydration may occur.

300 mg armodafinil This dose already exceeds the recommended one, so it is worth resorting to it only in exceptional cases. For example, when it is necessary to maintain an increased concentration for 18 or more hours. It is essentially a double dose of armodafinil, so it should be taken with extreme caution. It is better to divide it into several doses, as side effects may occur, but they do not pose a serious health risk. 300 mg modafinil Again, this is a large dose of the drug, so it should be taken with caution. After such an amount of the drug, an impeccable concentration is guaranteed for at least the next 18 hours. But it is important to consider that against the background of such a dose, side effects, including nausea, may already appear. It is better to divide this dosage into several doses.

400 mg modafinil If you need to stay awake for 24 hours, then 400 mg of modafinil will help you with this. But with such a dosage, you must be extremely careful if you are not used to the drug. As in previous cases, this dose is best divided into several doses. It is categorically contraindicated for regular use.

Dosing
Course with Modafinil for women
Side Effect of Modafinil